| 1970 | The Faculty Association was established. Aurelio Calderon became the first Faculty Association president. |
| 1971 | A Ford Foundation grant enabled the University to hook up one terminal on campus to a computer owned by Standford. |
The Center was called the De La Salle Computer Center. |
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| 1973 | De La Salle opened its campus to female students. |
| The College of Industrial Technology opened. | |
| A double degree Liberal Arts-Commerce (LIACOM) program was established. | |
| 1974 | The South Manila Inter-Institutional Consortium composed of De La Salle University, Philippine Christian College, Philippine Normal College, St. Scholastica’s College, and St. Paul College was established. |
| 1975 | De La Salle College was granted university status under the presidency of Brother H. Gabriel Connon FSC. |
| The director continued to be the religious superior of the Brothers’ community, and the president as the chief executive officer of De La Salle University, Inc. under a Board of Trustees (BOT), composed of five Brothers and ten laymen. The BOT reported to the corporation consisting of 51% Brothers and 49% laymen. | |
| 1976 | Juan Y. Medrano, who served De La Salle University for more than 50 years as a Grade School teacher, was given a “Letter of Affiliation to the Institute of the Brothers of the Christian Schools.” It was the highest honor being conferred to lay partners by the Brothers’ Superior General in Reims. |
| 1977 | The Office of Research was established. |
| 1978 | Br. Alphonsus Bloemen Hall was built. It became popularly known as the College Canteen. |
| De La Salle University started phasing out the Grade School Department with the intention of transferring it to the De La Salle-Zobel campus in Alabang, Muntinlupa. | |
| Br. Andrew Gonzalez FSC was named University President. He would serve until1991. | |
| 1979 | The Br. Gabriel Connon FSC Hall for the offices of the Student Personnel Services (SPS) and student organizations and the William J. Shaw Hall for faculty rooms were built. |